Article
What will whole genome searches for susceptibility genes for common complex disease offer to clinical practice?
Journal of internal medicine - 1 Jan 2008
Lango H, Weedon M N
Abstract excerpt
In the developed world the majority of disease results from common, but complex disorders such as diabetes, obesity and cancer. Genetic variation explains a large proportion of an individual's risk of developing these diseases; however, success in identifying the particular gene variants involved has been limited. Recent advances in high-throughput genotyping technology, and a better understanding of the genetic...
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