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Article

An Overview of Genome-Wide Association Studies.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Chang Michelle, He Lin, Cai Lei

Abstract excerpt

Genome-wide association study (GWAS) is a powerful study design to identify genetic variants of a trait and, in particular, detect the association between common single-nucleotide polymorphisms (SNPs) and common human diseases such as heart disease, inflammatory bowel disease, type 2 diabetes, and psychiatric disorders. The standard strategy of population-based case-control studies for GWAS is illustrated in this...

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PMID: 29536439
DOI: 10.1007/978-1-4939-7717-8_6

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