Article
Human adenoviral DNA association with nucleosomes containing histone variant H3.3 during the early phase of infection is not dependent on viral transcription or replication.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Dec 2018
Giberson Andrea N, Saha Bratati, Campbell Kalisa, Christou Carin, Poulin Kathy L, Parks Robin J
Abstract excerpt
Adenovirus (Ad) DNA undergoes dynamic changes in protein association as the virus progresses through its replicative cycle. Within the virion, the Ad DNA associates primarily with the virus-encoded, protamine-like protein VII. During the early phase of infection (∼6 h), the viral DNA showed declining association with VII, suggesting that VII was removed from at least some regions of the viral DNA. Within 6 h, the...
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