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Article

Temporal Dynamics of Cytomegalovirus Chromatin Assembly in Productively Infected Human Cells

12 Sept 2008

Abstract excerpt

The genomes of herpesviruses, including human cytomegalovirus (CMV), are double-stranded DNA molecules maintained as episomes during infection. The viral DNA lacks histones when encapsidated in the virion. However, it has been found histone associated inside infected cells, implying unidentified chromatin assembly mechanisms. Our results indicate that components of the host cell nucleosome deposition machinery...

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PMID: 18786996
DOI: 10.1128/jvi.01218-08

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