Binding modes of the precursor of adenovirus major core protein VII to DNA and template activating factor I: implication for the mechanism of remodeling of the adenovirus chromatin.

Abstract excerpt

Template Activating Factor (TAF) I remodels the adenovirus (Ad) core structure composed of the Ad genome DNA and basic viral core proteins and stimulates in vitro DNA replication and transcription of the Ad core. We have recently reported that TAF-I binds to major core protein VII and forms DNA-protein VII-TAF-I ternary complexes in vitro and in vivo. Further to understand the mechanism of remodeling of the Ad...

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