Article
Somatic mutations in benign breast disease tissue and risk of subsequent invasive breast cancer.
British journal of cancer - 1 Jun 2018
Rohan Thomas E, Miller Christopher A, Li Tiandao, Wang Yihong, Loudig Olivier, Ginsberg Mindy, Glass Andrew, Mardis Elaine
Abstract excerpt
BACKGROUND: Insights into the molecular pathogenesis of breast cancer might come from molecular analysis of tissue from early stages of the disease. METHODS: We conducted a case-control study nested in a cohort of women who had biopsy-confirmed benign breast disease (BBD) diagnosed between 1971 and 2006 at Kaiser Permanente Northwest and who were followed to mid-2015 to ascertain subsequent invasive breast cancer...
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