Article
Association Between Promoter Polymorphisms in CD46 and CD59 in Kidney Donors and Transplant Outcome.
Frontiers in immunology - 1 Jan 2018
Michielsen Laura A, van Zuilen Arjan D, Kardol-Hoefnagel Tineke, Verhaar Marianne C, Otten Henny G
Abstract excerpt
Complement regulating proteins, including CD46, CD55, and CD59, protect cells against self-damage. Because of their expression on the donor endothelium, they are hypothesized to be involved in accommodation. Polymorphisms in their promoter regions may affect their expression. The aim of this study was to investigate if donor polymorphisms in complement regulating proteins influence kidney transplant outcomes. We...
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