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Article

Nonhuman Primate Models of Huntington's Disease and Their Application in Translational Research.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Aron Badin Romina

Abstract excerpt

Huntington's disease (HD) is a monogenic, autosomal dominant inherited fatal disease that affects 1 in 10,000 people worldwide. Given its unique genetic characteristics, HD would appear as one of the most straightforward neurodegenerative diseases to replicate in animal models. Indeed, mutations in the HTT gene have been used to generate a variety of animal models that display differential pathologies and have...

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Source

Identifiers

PMID: 29856024
DOI: 10.1007/978-1-4939-7825-0_14

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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