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Article

Mouse models of Huntington disease: variations on a theme.

Disease models & mechanisms - 1 Jan 2000

Ehrnhoefer Dagmar E, Butland Stefanie L, Pouladi Mahmoud A, Hayden Michael R

Abstract excerpt

An accepted prerequisite for clinical trials of a compound in humans is the successful alleviation of the disease in animal models. For some diseases, however, successful translation of drug effects from mouse models to the bedside has been limited. One question is whether the current models accu...

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Identifiers

PMID: 19259385
DOI: 10.1242/dmm.002451
PMCID: PMC2650190

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19259385-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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