Article
Replicating Huntington's disease phenotype in experimental animals.
Progress in neurobiology - 1 Dec 1999
Brouillet E, Condé F, Beal M F, Hantraye P
Abstract excerpt
Huntington's disease (HD) is an inherited, autosomal dominant, neurodegenerative disorder characterized by involuntary choreiform movements, cognitive decline and a progressive neuronal degeneration primarily affecting the striatum. There is at present no effective therapy against this disorder....
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