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Article

Large-Brained Animal Models of Huntington's Disease: Sheep.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Morton A J

Abstract excerpt

The limitations of using small-brained rodents to model diseases that affect large-brain humans are becoming increasingly obvious as novel therapies emerge. Huntington's disease (HD) is one such disease. In recent years, the desirability of a large-brained, long-lived animal model of HD for preclinical testing has changed into a necessity. Treatment involving gene therapy in particular presents delivery...

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PMID: 29856022
DOI: 10.1007/978-1-4939-7825-0_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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