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Article

The 13C hyperpolarized pyruvate generated by ParaHydrogen detects the response of the heart to altered metabolism in real time.

Scientific reports - 30 May 2018

Cavallari Eleonora, Carrera Carla, Sorge Matteo, Bonne Gisèle, Muchir Antoine, Aime Silvio, Reineri Francesca

Abstract excerpt

Many imaging methods have been proposed to act as surrogate markers of organ damage, yet for many candidates the essential biomarkers characteristics of the injured organ have not yet been described. Hyperpolarized [1-13C]pyruvate allows real time monitoring of metabolism in vivo. ParaHydrogen Induced Polarization (PHIP) is a portable, cost effective technique able to generate 13C MR hyperpolarized molecules...

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Identifiers

PMID: 29849091
DOI: 10.1038/s41598-018-26583-2
PMCID: PMC5976640

Genes

PHIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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