Article
T<sub>2</sub> relaxation times of <sup>13</sup>C metabolites in a rat hepatocellular carcinoma model measured <i>in vivo</i> using <sup>13</sup>C‐MRS of hyperpolarized [1‐<sup>13</sup>C]pyruvate
19 Feb 2010
Abstract excerpt
A single-voxel Carr-Purcell-Meibloom-Gill sequence was developed to measure localized T(2) relaxation times of (13)C-labeled metabolites in vivo for the first time. Following hyperpolarized [1-(13)C]pyruvate injections, pyruvate and its metabolic products, alanine and lactate, were observed in the liver of five rats with hepatocellular carcinoma and five healthy control rats. The T(2) relaxation times of alanine...
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