Article

Evidence of Lactate Shuttling in the Human Brain using Hyperpolarized <sup>13</sup> C-MRI

2023-01-16

Abstract excerpt

<h4>Purpose</h4> To test the hypothesis that lactate shuttling contributes to the 13 C-lactate and 13 C-bicarbonate signal observed in the awake human brain using hyperpolarized 13 C MRI. <h4>Methods</h4> Healthy human volunteers (n = 6) were scanned twice using hyperpolarized 13 C-MRI, with reduced radiofrequency saturation of 13 C-lactate on one set of scans. 13 C-lactate, 13 C-bicarbonate, and 13 C-p...

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Literature Corpus work: 571b1224-62fe-5d24-8ade-587ac02f1d47
DOI: 10.1101/2023.01.13.523957

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