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Article

Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity.

Drug delivery - 1 Nov 2018

Taguchi Kazuaki, Nagao Saori, Maeda Hitoshi, Yanagisawa Hiroki, Sakai Hiromi, Yamasaki Keishi, Wakayama Tomohiko, Watanabe Hiroshi, Otagiri Masaki, Maruyama Toru

Abstract excerpt

Macrophages play a central role in various inflammatory disorders and are broadly divided into two subpopulations, M1 and M2 macrophage. In the healing process in acute inflammatory disorders, shifting the production of M1 macrophages to M2 macrophages is desirable, because M1 macrophages secrete pro-inflammatory cytokines, whilst the M2 variety secrete anti-inflammatory cytokines. Previous findings indicate that...

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Identifiers

PMID: 29847178
DOI: 10.1080/10717544.2018.1477860
PMCID: PMC6058524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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