Article
Polygenic Risk Scores, School Achievement, and Risk for Schizophrenia: A Danish Population-Based Study.
Biological psychiatry - 1 Nov 2018
Sørensen Holger J, Debost Jean-Christophe, Agerbo Esben, Benros Michael E, McGrath John J, Mortensen Preben Bo, Ranning Anne, Hjorthøj Carsten, Mors Ole, Nordentoft Merete, Petersen Liselotte
Abstract excerpt
BACKGROUND: Studies have suggested that poor school achievement is associated with increased risk of schizophrenia; however, the possible genetic contribution to this association is unknown. We investigated the possible effect of the polygenic risk score (PRS) for schizophrenia (PRSSCZ) and for educational attainment (PRSEDU) on the association between school performance and later schizophrenia. METHODS: We...
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