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Article

Generation of Smurf2 Conditional Knockout Mice.

International journal of biological sciences - 1 Jan 2018

Tang Yi, Tang Liu-Ya, Xu Xuan, Li Cuiling, Deng Chuxia, Zhang Ying E

Abstract excerpt

Smad ubiquitin regulatory factor 2 (Smurf2) is a HECT domain-containing E3 ubiquitin ligase. Together with its closely related homolog Smurf1, Smurf2 was initially recognized as a negative regulator of transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) signaling, but subsequent studies have expanded its function to regulate many different signaling pathways and play important roles in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29805305
DOI: 10.7150/ijbs.24303
PMCID: PMC5968846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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