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Article

Genetic Signatures: CD44 Single-Nucleotide Polymorphisms Affect Cell Surface Expression and Elevate Risk in Head and Neck Squamous Cell Carcinoma.

JCO global oncology - 1 Oct 2024

Kashif Muhammad, Jahan Shah, Minhas Sadia, Amar Ali, Tahir Romeeza, Nisar Haseeb, Shehzad Faheem, Nagi Abdul Hanan, Afzal Nadeem

Abstract excerpt

PURPOSE: This study aimed to investigate the impact of single-nucleotide polymorphisms (SNPs) in the CD44 gene, specifically in the 3'UTR region (rs13347) and intronic region (rs187115), on the cell surface expression of CD44 protein and the risk of development of head and neck squamous cell carcinoma (HNSCC). MATERIALS AND METHODS: The study involved analysis of 85 samples and 85 healthy controls....

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Source

Identifiers

PMID: 39481067
DOI: 10.1200/GO.24.00084

Genes

CD44
SI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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