Article
CD44 single nucleotide polymorphism and isoform switching may predict gastric cancer recurrence.
Journal of surgical oncology - 1 Nov 2015
Suenaga Masaya, Yamada Suguru, Fuchs Bryan C, Fujii Tsutomu, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Tanabe Kenneth K, Kodera Yasuhiro
Abstract excerpt
BACKGROUND AND OBJECTIVES: The clinical implications of single nucleotide polymorphisms (SNPs) in CD44 remain unclear. This study examined the relationships of CD44 SNPs with clinicopathological parameters and prognosis in Japanese gastric cancer patients. METHODS: The CD44 SNPs were analyzed in 11 gastric cancer cell lines and 517 clinical specimens. The expression of CD44 standard (CD44s) and CD44 variant 9...
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