Article
Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a meta-analysis.
Oncotarget - 8 Nov 2016
Chandra Vishal, Lee Yun-Mi, Gupta Usha, Mittal Balraj, Kim Jong Joo, Rai Rajani
Abstract excerpt
CD44 is a well-established cancer stem cell marker playing a crucial role in tumor metastasis, recurrence and chemo-resistance. Genetic variants of CD44 have been shown to be associated with susceptibility to various cancers; however, the results are confounding. Hence, we performed a meta-analysis to clarify these associations more accurately. Overall, rs13347 (T vs. C: OR=1.30, p=<0.004, pcorr=0.032; CT vs. CC:...
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