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Human genome variability, natural selection and infectious diseases.

Current opinion in immunology - 1 Oct 2014

Fumagalli Matteo, Sironi Manuela

Abstract excerpt

The recent availability of large-scale sequencing DNA data allowed researchers to investigate how genomic variation is distributed among populations. While demographic factors explain genome-wide population genetic diversity levels, scans for signatures of natural selection pinpointed several regions under non-neutral evolution. Recent studies found an enrichment of immune-related genes subjected to natural...

Topics

Animals
Genetic Variation
Genome, Human
Humans
Infections
Selection, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24880709
DOI: 10.1016/j.coi.2014.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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