Article
Human genome variability, natural selection and infectious diseases.
Current opinion in immunology - 1 Oct 2014
Fumagalli Matteo, Sironi Manuela
Abstract excerpt
The recent availability of large-scale sequencing DNA data allowed researchers to investigate how genomic variation is distributed among populations. While demographic factors explain genome-wide population genetic diversity levels, scans for signatures of natural selection pinpointed several regions under non-neutral evolution. Recent studies found an enrichment of immune-related genes subjected to natural...
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