Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach.

PLoS genetics - 19 Feb 2010

Fumagalli Matteo, Pozzoli Uberto, Cagliani Rachele, Comi Giacomo P, Bresolin Nereo, Clerici Mario, Sironi Manuela

Abstract excerpt

Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants. Virus diversity (the number of different viruses in a geographic region) was used to measure virus-driven selective pressure. Results showed an excess of variants correlated with virus diversity in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genetics, Population

Share to Genome-Wide Association Study

Share to Selection, Genetic

Share to Virus Diseases

Share to Viruses

Source

Open in PubMed Open full text

Identifiers

PMID: 20174570
DOI: 10.1371/journal.pgen.1000849
PMCID: PMC2824813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach.PMID 20174570Read ↗

Human genome variability, natural selection and infectious diseases.Semantic proximity Read ↗

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.Semantic proximity Read ↗

A genome-wide perspective of human diversity and its implications in infectious disease.Semantic proximity Read ↗

Human Genetic Determinants of Viral Diseases.Semantic proximity Read ↗

Trends in population-based studies of human genetics in infectious diseases.Semantic proximity Read ↗

Exploring the interactions between the human and viral genomes.Semantic proximity Read ↗

Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility.Semantic proximity Read ↗

Hypervariable loci in the human gut virome.Semantic proximity Read ↗

European genetic diversity and susceptibility to pathogens.Semantic proximity Read ↗

Genome–virome interactions: examining the role of common viral infections in complex diseaseSemantic proximity Read ↗

Host-pathogen interactions revealed by human genome-wide surveys.Semantic proximity Read ↗

Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.