Article
Evidence for polygenic adaptation to pathogens in the human genome.
Molecular biology and evolution - 1 Jul 2013
Daub Josephine T, Hofer Tamara, Cutivet Emilie, Dupanloup Isabelle, Quintana-Murci Lluis, Robinson-Rechavi Marc, Excoffier Laurent
Abstract excerpt
Most approaches aiming at finding genes involved in adaptive events have focused on the detection of outlier loci, which resulted in the discovery of individually "significant" genes with strong effects. However, a collection of small effect mutations could have a large effect on a given biologic...
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