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Article

Apolipoprotein E region molecular signatures of Alzheimer's disease.

Aging cell - 1 Aug 2018

Kulminski Alexander M, Huang Jian, Wang Jiayi, He Liang, Loika Yury, Culminskaya Irina

Abstract excerpt

Although the APOE region is the strongest genetic risk factor for Alzheimer's diseases (ADs), its pathogenic role remains poorly understood. Elucidating genetic predisposition to ADs, a subset of age-related diseases characteristic for postreproductive period, is hampered by the undefined role of evolution in establishing molecular mechanisms of such diseases. This uncertainty is inevitable source of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29797398
DOI: 10.1111/acel.12779
PMCID: PMC6052488

Genes

APOE
APOC1
BCAM
NECTIN2
TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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