Article
Mouse-to-mouse variation in maturation heterogeneity of smooth muscle cells.
Lab on a chip - 26 Jun 2018
Rosàs-Canyelles Elisabet, Dai Tiffany, Li Song, Herr Amy E
Abstract excerpt
Smooth muscle cell (SMC) heterogeneity plays an important role in vascular remodeling, a life-threatening hallmark of many vascular diseases. However, the characterization of SMCs at the single-cell level is stymied by drawbacks of contemporary single-cell protein measurements, including antibody probe cross-reactivity, chemical fixation artifacts, limited isoform-specific probes, low multiplexing and difficulty...
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