Article
The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden: the GLACIER Study.
International journal of obesity (2005) - 1 Apr 2019
Chen Yan, Estampador Angela C, Keller Maria, Poveda Alaitz, Dalla-Riva Jonathan, Johansson Ingegerd, Renström Frida, Kurbasic Azra, Franks Paul W, Varga Tibor V
Abstract excerpt
BACKGROUND: Recent analyses in Greenlandic Inuit identified six genetic polymorphisms (rs74771917, rs3168072, rs12577276, rs7115739, rs174602 and rs174570) in the fatty acid desaturase gene cluster (FADS1-FADS2-FADS3) that are associated with multiple metabolic and anthropometric traits. Our objectives were to systematically assess whether dietary polyunsaturated fatty acid (PUFA) intake modifies the associations...