Article
FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies.
PloS one - 1 Jan 2012
Standl Marie, Lattka Eva, Stach Barbara, Koletzko Sibylle, Bauer Carl-Peter, von Berg Andrea, Berdel Dietrich, Krämer Ursula, Schaaf Beate, Röder Stefan, Herbarth Olf, Buyken Anette, Drogies Tim, Thiery Joachim, Koletzko Berthold, Heinrich Joachim
Abstract excerpt
BACKGROUND: Elevated cholesterol levels in children can be a risk factor for cardiovascular diseases in later life. In adults, it has been shown that blood lipid levels are strongly influenced by polymorphisms in the fatty acid desaturase (FADS) gene cluster in addition to nutritional and other exogenous and endogenous determinants. Our aim was to investigate whether lipid levels are determined by the FADS...
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