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Article

Do Genetic Factors Modify the Relationship Between Obesity and Hypertriglyceridemia? Findings From the GLACIER and the MDC Studies.

Circulation. Cardiovascular genetics - 1 Apr 2016

Ali Ashfaq, Varga Tibor V, Stojkovic Ivana A, Schulz Christina-Alexandra, Hallmans Göran, Barroso Inês, Poveda Alaitz, Renström Frida, Orho-Melander Marju, Franks Paul W

Abstract excerpt

BACKGROUND: Obesity is a major risk factor for dyslipidemia, but this relationship is highly variable. Recently published data from 2 Danish cohorts suggest that genetic factors may underlie some of this variability. METHODS AND RESULTS: We tested whether established triglyceride-associated loci modify the relationship of body mass index (BMI) and triglyceride concentrations in 2 Swedish cohorts (the...

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PMID: 26865658
DOI: 10.1161/CIRCGENETICS.115.001218

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