Article
Cell-Cycle Regulation of Dynamic Chromosome Association of the Condensin Complex.
Cell reports - 22 May 2018
Thadani Rahul, Kamenz Julia, Heeger Sebastian, Muñoz Sofía, Uhlmann Frank
Abstract excerpt
Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from the compaction of interphase chromatin by the condensin complex. Condensin is a member of the structural maintenance of chromosomes (SMC) family of ATPases, large ring-shaped protein assemblies that entrap DNA to establish chromosomal interactions. Here, we use the budding yeast Saccharomyces cerevisiae to dissect the role of...
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