Article
Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome.
Molecular and cellular biology - 1 Aug 2005
Wang Bi-Dar, Eyre David, Basrai Munira, Lichten Michael, Strunnikov Alexander
Abstract excerpt
Mitotic chromosome condensation is chiefly driven by the condensin complex. The specific recognition (targeting) of chromosomal sites by condensin is an important component of its in vivo activity. We previously identified the rRNA gene cluster in Saccharomyces cerevisiae as an important condensin-binding site, but both genetic and cell biology data suggested that condensin also acts elsewhere. In order to...
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