Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vitamin D pathway gene polymorphisms affecting daclatasvir plasma concentration at 2 weeks and 1 month of therapy.

Pharmacogenomics - 1 Jun 2018

Cusato Jessica, De Nicolò Amedeo, Boglione Lucio, Favata Fabio, Ariaudo Alessandra, Pinna Simone Mornese, Carcieri Chiara, Guido Federica, Cariti Giuseppe, Di Perri Giovanni, D'Avolio Antonio

Abstract excerpt

AIM: Vitamin D (VD) influences genetic expression through its receptor (VDR). VD pathway gene polymorphisms seem to influence antiviral drug pharmacokinetics and therapeutic outcome/toxicity. We investigated the association between daclatasvir (DCV) plasma concentrations and genetic variants (SNPs) associated with the VD pathway. PATIENTS & METHODS: Chronic hepatitis C patients treated with DCV from 2014 to 2016...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Carbamates

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Imidazoles

Share to Pyrrolidines

Share to Receptors, Calcitriol

Share to Valine

Share to Vitamin D

Source

Identifiers

PMID: 29790402
DOI: 10.2217/pgs-2018-0009

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vitamin D pathway gene polymorphisms affecting daclatasvir plasma concentration at 2 weeks and 1 month of therapy.PMID 29790402Read ↗

Vitamin D pathway genetic variants are able to influence sofosbuvir and its main metabolite pharmacokinetics in HCV mono-infected patients.Semantic proximity Read ↗

Association of vitamin D pathway SNPs and clinical response to interferon in a cohort of HBeAg-negative patients.Semantic proximity Read ↗

Impact of vitamin D receptor and binding protein gene polymorphisms in clinical and laboratory data of HCV patients: Cross sectional study.Semantic proximity Read ↗

Vitamin D pathway gene variants and HCV-2/3 therapy outcomes.Semantic proximity Read ↗

Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients.Semantic proximity Read ↗

Altered Vitamin D Receptor Expression in Apa-I (rs7975232) Allelic Variants-A Probable Risk Factor for Susceptibility to Hepatitis B Virus Infection and Disease Progression.Semantic proximity Read ↗

Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.Semantic proximity Read ↗

Influence of vitamin D-related gene polymorphisms (CYP27B and VDR) on the response to interferon/ribavirin therapy in chronic hepatitis C.Semantic proximity Read ↗

Genetic polymorphisms of vitamin D pathway predict antiviral treatment outcome in slow responder naïve patients with chronic hepatitis C.Semantic proximity Read ↗

Genetic variations in vitamin D receptor were associated with the outcomes of hepatitis C virus infection among Chinese population.Semantic proximity Read ↗

Association of Vitamin-D Receptor (Vdr), Gc-globulin and Cyp2r1 Polymorphism With Progression of Hbv Related Liver Disease Along With an Exclusive Svm Based Disease Prediction ModelSemantic proximity Read ↗

Vitamin D pathway gene polymorphisms and hepatocellular carcinoma in chronic hepatitis C-affected patients treated with new drugs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.