Article
Association of vitamin D pathway SNPs and clinical response to interferon in a cohort of HBeAg-negative patients.
Pharmacogenomics - 1 May 2017
Cusato Jessica, Boglione Lucio, De Nicolò Amedeo, Imbornone Rosaria, Cardellino Chiara Simona, Ghisetti Valeria, Carcieri Chiara, Cariti Giuseppe, Di Perri Giovanni, D'Avolio Antonio
Abstract excerpt
AIM: Vitamin D modulates biological processes; an influence of vitamin D levels and genetic variants was identified concerning hepatitis B virus infection. We evaluated the role of some SNPs of vitamin D pathway genes in some clinical features of hepatitis B affected patients treated with pegylated interferon. METHODS: We investigated SNPs in IL-28B, CYP27B1, CYP27A1, CYP24A1, VDBP and VDR genes, through...
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