Article
Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients.
BMC gastroenterology - 17 Apr 2017
Thanapirom Kessarin, Suksawatamnuay Sirinporn, Sukeepaisarnjaroen Wattana, Tangkijvanich Pisit, Treeprasertsuk Sombat, Thaimai Panarat, Wasitthankasem Rujipat, Poovorawan Yong, Komolmit Piyawat
Abstract excerpt
BACKGROUND: Patients with chronic hepatitis C (HCV) infection have high prevalence of vitamin D deficiency. Genome-wide association study data has showed that several genetic variants within vitamin D cascade affect vitamin D function. This study aimed to determine whether genetic polymorphisms of genes in the vitamin D pathway are associated with treatment responses to pegylated interferon (PEG-IFN)-based...
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