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Article

Influence of vitamin D-related gene polymorphisms (CYP27B and VDR) on the response to interferon/ribavirin therapy in chronic hepatitis C.

PloS one - 1 Jan 2013

García-Martín Elena, Agúndez José A G, Maestro María L, Suárez Avelina, Vidaurreta Marta, Martínez Carmen, Fernández-Pérez Cristina, Ortega Luis, Ladero José M

Abstract excerpt

BACKGROUND AND AIMS: Vitamin D exerts immunomodulatory effects on the host response against infection with hepatitis C virus (HCV). This study was performed to assess the putative influence of polymorphisms in vitamin D-related genes on the response to antiviral therapy in patients with chronic hepatitis C (CHC). METHODS: Single nucleotide polymorphisms (SNPs) in CYP27B-1260 gene promoter (rs10877012AC) and in...

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
Share to Antiviral Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferon-alpha

Share to Receptors, Calcitriol

Share to Ribavirin

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Source

Open in PubMed Open full text

Identifiers

PMID: 24073221
DOI: 10.1371/journal.pone.0074764
PMCID: PMC3779247

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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