Article
Altered Vitamin D Receptor Expression in Apa-I (rs7975232) Allelic Variants-A Probable Risk Factor for Susceptibility to Hepatitis B Virus Infection and Disease Progression.
Viral immunology - 1 Oct 2023
Kalita Manash Jyoti, Kalita Simanta, Das Partha Pratim, Hazarika Gautam, Dutta Kalpajit, Deka Ankur Jyoti, Bhuyan Juchidananda, Idris Md Ghaznavi, Choudhury Bikash Narayan, Kaur Harpreet, Medhi Subhash
Abstract excerpt
Vitamin D exerts its antiviral effect through vitamin D receptor (VDR)/retinoid X receptor-mediated host immunomodulation. Besides the downregulation of VDR expression, its polymorphism was also observed among hepatitis B virus (HBV)-positive patients. To understand the possible link between VDR polymorphism and its altered expression during HBV infection and disease progression, VDR Apa-I [rs7975232 (C>A)]...
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