Article
Genetic variations in vitamin D receptor were associated with the outcomes of hepatitis C virus infection among Chinese population.
Journal of human genetics - 1 Feb 2016
Wu Meng-ping, Zhang Jin-wei, Huang Peng, Han Ya-ping, Zhang Yun, Peng Zhi-hang, Wang Jie, Zhu Ping, Su Jing, Yu Rong-bin, Li Jun, Yue Ming
Abstract excerpt
Vitamin D has been considered as an immune modulator, and exerted the effect through the vitamin D receptor (VDR). This study investigated the associations of single-nucleotide polymorphisms (SNPs) of VDR with the outcomes of Hepatitis C virus (HCV) infection. Three SNPs (rs2228570, rs757343 and rs739837) were genotyped by TaqMan assay among Chinese population, including 538 HCV spontaneous clearance subjects,...
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