Article
Well-Annotated microRNAomes Do Not Evidence Pervasive miRNA Loss.
Genome biology and evolution - 1 Jun 2018
Tarver James E, Taylor Richard S, Puttick Mark N, Lloyd Graeme T, Pett Walker, Fromm Bastian, Schirrmeister Bettina E, Pisani Davide, Peterson Kevin J, Donoghue Philip C J
Abstract excerpt
microRNAs are conserved noncoding regulatory factors implicated in diverse physiological and developmental processes in multicellular organisms, as causal macroevolutionary agents and for phylogeny inference. However, the conservation and phylogenetic utility of microRNAs has been questioned on evidence of pervasive loss. Here, we show that apparent widespread losses are, largely, an artefact of poorly sampled...
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