Article
Altered miRNA repertoire in the simplified chordate, Oikopleura dioica.
Molecular biology and evolution - 1 Jun 2008
Fu Xianghui, Adamski Marcin, Thompson Eric M
Abstract excerpt
Recent studies reveal correlation between microRNA (miRNA) innovation and increased developmental complexity. This is exemplified by dramatic expansion of the miRNA inventory in vertebrates, a lineage where genome duplication has played a significant evolutionary role. Urochordates, the closest extant group to the vertebrates, exhibit an opposite trend to genome and morphological simplification. We show that the...
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