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Article

Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee.

Arthritis and rheumatism - 1 Jan 2007

Valdes Ana M, Loughlin John, Oene Mark Van, Chapman Kay, Surdulescu Gabriela L, Doherty Michael, Spector Tim D

Abstract excerpt

OBJECTIVE: To assess whether the association of genetic polymorphisms with osteoarthritis (OA) in other populations could be replicated in a large, multicenter, mixed-sex, case-control study of clinical knee OA. METHODS: Genetic polymorphisms in OA candidate genes were genotyped in 298 men and 305 women, ages 50-86 years, all of whom had a diagnosis of knee OA as assessed clinically and radiographically, and in...

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Source

Identifiers

PMID: 17195216
DOI: 10.1002/art.22301

Genes

FRZB
ASPN
COMP
CALM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee.PMID 17195216Read ↗

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