Genetic association analysis of GDF5 and ADAM12 for knee osteoarthritis.

doi:10.1016/j.jbspin.2011.10.016

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Article

Genetic association analysis of GDF5 and ADAM12 for knee osteoarthritis.

Joint bone spine - 1 Oct 2012

Shin Min-Ho, Lee Sung-Ji, Kee Seung-Jung, Song Sang-Kook, Kweon Sun-Seog, Park Dong-Jin, Park Yong-Wook, Lee Shin-Seok, Kim Tae-Jong

Abstract excerpt

OBJECTIVES: To examine two single-nucleotide polymorphisms (SNPs) for their association with knee osteoarthritis (OA) susceptibility in Korean cohort. METHODS: Two thousand four hundred and sixty-two subjects aged 50 years and older were assessed for OA at the knee, were genotyped with two SNPs (GDF5; rs143383 and ADAM12; rs3740199). Radiographs were read by two examiners that used an atlas of radiographic...

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PMID: 22284607
DOI: 10.1016/j.jbspin.2011.10.016

Genes

ADAM12
GDF5

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