Article
Analyses of the Genetic Polymorphisms rs3740199 and rs1871054 of the ADAM12 Gene and the Alleles at the rs2073508 Loci of the TGFB1 Gene and Their Contribution to Susceptibility to Primary Knee Osteoarthritis.
Genetic testing and molecular biomarkers - 1 Jun 2020
Aguilar Muñiz Lizette Sarai, González Galarza Faviel Francisco, Arguello Astorga Rafael, Prieto Hinojosa Adria Imelda, Hernández Terán Fernando, Méndez Hernández Alejandra, Espino Silva Perla Karina, Blanco García Francisco Javier, Arellano Pérez Vertti Rubén Daniel
Abstract excerpt
Aims: To analyze the association of polymorphisms in the ADAM12 (rs3740199 and rs1871054) and TGFB1 (rs2073508) genes with knee osteoarthritis (KOA) in a population from northern Mexico. Methods: A total of 296 individuals were included in the study. Primary KOA was confirmed according to the criteria established by the American College of Rheumatology. A real-time PCR-based DNA genotyping method was used to...
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