Article
Strain-Specific Antagonism of the Human H1N1 Influenza A Virus against Equine Tetherin.
Viruses - 16 May 2018
Wang Meiyue, Zhang Zhenyu, Wang Xiaojun
Abstract excerpt
Tetherin/BST-2/CD317 is an interferon-induced host restriction factor that can block the budding of enveloped viruses by tethering them to the cell surface. Many viruses use certain proteins to counteract restriction by tetherin from their natural hosts, but not from other species. The influenza A virus (FLUAV) has a wide range of subtypes with different host tropisms. Human tetherin (huTHN) has been reported to...
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