Article
Antiviral potency and functional analysis of tetherin orthologues encoded by horse and donkey.
Virology journal - 27 Aug 2014
Yin Xin, Guo Miaomiao, Gu Qinyong, Wu Xingliang, Wei Ping, Wang Xiaojun
Abstract excerpt
BACKGROUND: Tetherin is an interferon-inducible host cell factor that blocks the viral particle release of the enveloped viruses. Most knowledge regarding the interaction between tetherin and viruses has been obtained using the primate lentiviral system. However, much less is known about the functional roles of tetherin on other lentiviruses. Equine infectious anemia virus (EIAV) is an important macrophage-tropic...
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