Article
A pilot study on interaction between donkey tetherin and EIAV stains with different virulent and replication characteristics.
Microbial pathogenesis - 1 May 2017
Yao Qiucheng, Ma Jian, Wang Xuefeng, Guo Miaomiao, Li Yanfei, Wang Xiaojun
Abstract excerpt
Tetherin (BST-2) is an important host restriction factor that can inhibit the release of a diverse array of enveloped viruses from infected cells. Conversely, to facilitate their release and spread, many viruses have evolved various strategies to overcome the antiviral effect of tetherin in a species-specific manner. During the development of an attenuated equine infectious anemia virus (EIAV) vaccine in our...
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