Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer.

doi:10.1002/ijc.31604

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Article

Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer.

International journal of cancer - 15 Oct 2018

Paumard-Hernández Beatriz, Calvete Oriol, Inglada Pérez Lucia, Tejero Héctor, Al-Shahrour Fátima, Pita Guillermo, Barroso Alicia, Carlos Triviño Juan, Urioste Miguel, Valverde Claudia, González Billalabeitia Enrique, Quiroga Vanesa, Francisco Rodríguez Moreno Juan, Fernández Aramburo Antonio, López Cristina, Maroto Pablo, Sastre Javier, José Juan Fita María, Duran Ignacio, Lorenzo-Lorenzo Isabel, Iranzo Patricia, García Del Muro Xavier, Ros Silverio, Zambrana Francisco, María Autran Ana, Benítez Javier

Abstract excerpt

Testicular germ cell tumors (TGCTs) are a clinically and pathologically heterogeneous disease, and little is known of its genetic basis. Only low susceptibility risk loci have been identified for both sporadic and familial cases. Therefore, we tried to identify new susceptibility genes responsible for familial testicular cancer that may contribute to increasing our knowledge about the genetic basis of the...

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Identifiers

PMID: 29761480
DOI: 10.1002/ijc.31604

Genes

DNAH7
EXO5
PLEC

Variants

Provenance

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