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Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment

2 Apr 2018

Abstract excerpt

Abstract Objective Changes in progranulin (GRN) expression have been hypothesized to alter risk for Alzheimer's disease (AD). We investigated the relationship between GRN expression in peripheral blood and clinical diagnosis of AD and mild cognitive impairment (MCI). Methods Peripheral blood progranulin gene expression was measured, using microarrays from Alzheimer's (n = 186), MCI (n = 118), and control (n =...

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PMID: 29761124
DOI: 10.1002/acn3.560

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