Article
Analysis of cancer-associated fibroblasts and the epithelial-mesenchymal transition in cutaneous basal cell carcinoma, squamous cell carcinoma, and malignant melanoma.
Human pathology - 1 Sept 2018
Sasaki Kousuke, Sugai Tamotsu, Ishida Kazuyuki, Osakabe Mitsumasa, Amano Hiroo, Kimura Hiroaki, Sakuraba Minoru, Kashiwa Katsuhiko, Kobayashi Seiichiro
Abstract excerpt
Activated cancer-associated fibroblasts (CAFs) and fibroblasts that have undergone the epithelial-mesenchymal transition (EMT) in cancer stroma contribute to tumor progression and metastasis. However, no reports have investigated the CAF phenotype and its clinicopathological relevance in cutaneous malignant tumors, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM)....
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