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The transcriptional landscape analysis of basal cell carcinomas reveals novel signalling pathways and actionable targets

10 May 2021

Abstract excerpt

Basal cell carcinoma (BCC) is the most common skin cancer and human malignancy. Although most BCCs are easily managed, some are aggressive locally, require Mohs micrographic surgery, or can even metastasize. In the latter, resistance to Sonic Hedgehog inhibitors may occur. Despite their frequent occurrence in clinical practice, their transcriptional landscape remains poorly understood. By analyzing BCC RNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33972406
DOI: 10.26508/lsa.202000651

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