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Article

Subtype-Specific Analyses Reveal Infiltrative Basal Cell Carcinomas Are Highly Interactive with their Environment.

The Journal of investigative dermatology - 1 Oct 2021

Villani Rehan, Murigneux Valentine, Alexis Josue, Sim Seen-Ling, Wagels Michael, Saunders Nicholas, Soyer H Peter, Parmentier Laurent, Nikolaev Sergey, Fink J Lynn, Roy Edwige, Khosrotehrani Kiarash

Abstract excerpt

Little is known regarding the molecular differences between basal cell carcinoma (BCC) subtypes, despite clearly distinct phenotypes and clinical outcomes. In particular, infiltrative BCCs have poorer clinical outcomes in terms of response to therapy and propensity for dissemination. In this project, we aimed to use exome sequencing and RNA sequencing to identify somatic mutations and molecular pathways leading...

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PMID: 33865912
DOI: 10.1016/j.jid.2021.02.760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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