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Article

Defects in pre-mRNA processing as causes of and predisposition to diseases.

DNA and cell biology - 1 Nov 2002

Stoilov Peter, Meshorer Eran, Gencheva Marieta, Glick David, Soreq Hermona, Stamm Stefan

Abstract excerpt

Humans possess a surprisingly low number of genes and intensively use pre-mRNA splicing to achieve the high molecular complexity needed to sustain normal body functions and facilitate responses to altered conditions. Because hundreds of thousands of proteins are generated by 25,000 to 40,000 genes, pre-mRNA processing events are highly important for the regulation of human gene expression. Both inherited and...

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Identifiers

PMID: 12489991
DOI: 10.1089/104454902320908450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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